RNA is the coded transcription of the information in DNA that is meticulously co-produced by the DNA and protein enzyme catalysts in a highly orchestrated symphony of intertwined labor and control. Truly stunning, it is a wonder to behold. RNA is not just a copy of DNA with a slightly different sugar molecule, one stranded not two, and using uracil (U) instead of thymine (T) to bind to adenine (A); it is that, but it is more. The mRNA strands are the transcribed blue prints sent out into the cytoplasm to be translated by the ribosome. The tRNA strands are individualized amino acid carriers that match up along the mRNA strand and co-catalyze the peptide bonded amino acid chains of protein construction. And, in a structural capacity, all ribonucleic protein (RNP) structures have their own RNA elements and parts; rRNA in ribosome and vRNA in vaults are examples. The code complexities are the same, but RNA is more of a worker and tool of the code than the repository of it. mRNA carries the intelligence out of the nucleus and into the cytoplasm where it is read and acted upon. tRNA is the labor force that coordinates and transports all the construction materials and facilitates their joining at the ribosome construction sites. Robert Holly (1962) solved the structure of tRNA, which looks a bit like a Celtic cross attaching its specific amino acid at its top and having at its base the nucleotide word that pairs with mRNA at a specific site on the ribosome. Lastly, the various possible roles of the RNA in RNP structures are driving much current research. Every thing we learn adds to a complexity that simply can not be reduced without serious damage to the organism. Indeed damage from toxins and mutations are some of the most heuristic objects and generators of this research, as is cancer and other diseases, all adding to our understanding of how these complex machines work and network.
RNA Complexity (ribonucleic acid) Newsletter
Written by xDICEx | Last Modified on: 2013-09-27 01:34:39 | Hits: 45